CGT Manufacturing | scale-up

05 Jul 2022

Scaling-up Versus Scaling-out: Here’s What You Need To Know

A lot of CDMO customers ask about scale-out and scale-up, and what app...

21 May 2021

Scaling-Up Production of Pluripotent Stem Cells Part 1: Begin with the End in Mind

Many emerging cell and gene therapies are aimed at using cell replacem...

30 Oct 2019

Concentration and Reformulation of Cellular Immunotherapies – A Major Downstream Processing Step

Cellular immunotherapies (e.g. CAR-T cells) are primarily used as an a...

30 Oct 2019

How To Scale-Up Lentiviral Vector Production Part 2: Considerations for Downstream Processing

In Part 1 of our series on lentiviral vector (LVV) manufacturing we co...

29 Oct 2019

How to Scale-Up Lentiviral Vector Production Part 1: Considerations for Upstream Processing

Lentiviral vectors (LVV) are a key component in the production of cell...

24 Oct 2019

What is a Bioreactor and How is it Used in Cell and Gene Therapy?

Simply put, a bioreactor is a stand-alone cell culture vessel enabled ...

MaRS Centre, West Tower
661 University Avenue, Suite 1002
Toronto, Ontario M5G 1M1 Canada
t: 416-978-3751
f: 416-978-1368

We wish to acknowledge this land on which CCRM operates. For thousands of years, it has been the traditional land of the Huron-Wendat, the Seneca, and the Mississaugas of the Credit. Today, this meeting place is still the home to many Indigenous people from across Turtle Island and we are grateful to have the opportunity to work on this land.